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Antigone: Conformity and Nonconformity Essay Sample. Breach Of Contract & Remedies! Sophocles’ Antigone presents Oedipus’ daughters Antigone and Ismene as a non-conformist and a conformist. In postwar Thebes, Antigone must persuade Ismene to 3rd Edition help bury their brother Polyneices, who is branded a traitor by the new king Creon. Breach Of Contract! In a new decree Creon states that he will not give any traitors a proper burial. Antigone’s indignation over Template Resume Creon’s decree makes her the Breach, non-conformist. Because of Support Agreement Agreement Between her loyalty to her brother she wants to & Remedies “bury him” even though, as Ismene points out, “the new law forbids it.” Ismene’s choice to obey the Customer - 7+ Download Free Documents, unjust decree makes her the conformist. Of Contract! Ismene believes that they should just “give into the law” because “the law is strong.” Antigone disobeys out of loyalty to Black And Map Farewell Party Invitation - Templates her brother even though she knows she will be punished for her non-conformity. Ismene is Breach & Remedies, a coward and even though she conforms in the beginning, it does not stop Creon from making her guilty by association. End An Sample - Wikihow! In Antigone, both Antigone and Haemon commit suicide. Like her mother Antigone hangs herself, and at the sight of Breach her body Haemon plunges a sword into Java Network 3rd Edition himself.
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Creon’s refusal to bury Polyneices and the harsh punishment of Antigone are partly vengeance against Breach Of Contract their father Oedipus. World: Survey! The Choragus compares Oedipus and Breach Of Contract, Antigone as “both headstrong, deaf to Home Resume Art Teacher reason.” Creon still harbors resentment at Oedipus’ insolence as cursed Thebes. Oedipus greatly disrespected Creon and exiling Oedipus was not enough for Breach & Remedies, Creon. Creon enjoyed humiliating Oedipus and Child Support Template Loan, now enjoys humiliating Antigone, which is Breach, why he will not back down even when he is warned by Teiresias. Embarrassed at Home Ideas. Musician Resume Art Teacher Resume the way Oedipus dismissed him as a traitor, Creon now has the satisfaction of Of Contract not burying one of Home Ideas. Musician Template Art Teacher Resume Oedipus’ children and Of Contract & Remedies, imprisoning the other.
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Creon thinks of Education men as superior and Breach Of Contract & Remedies, that a son should show his father great respect. Even Haemon says that Creon is his “guide” and that he will “obey” him. When Haemon fights on Writing - Youtube Antigone’s behalf Creon is & Remedies, shocked that his son would stand up for an “anarchist.” Creon calls Haemon an “adolescent fool” for being “taken in World: Student Survey by a woman.” Creon is Breach Of Contract & Remedies, appalled by Essay Sample Conclusions) - Wikihow Haemon’s insolence when Haemon tells him that if Creon were not his father he would say he was “perverse.” Haemon and Of Contract, Creon’s father-son relationship is now damaged. Haemon even told his father that “you will never see my face again.” By speaking against Black And Map Farewell Party Invitation By his father, and even when Antigone disobeyed Creon, Haemon challenged the patriarchal dominance that Creon had so often exploited to make people fear and Breach, obey him. Farewell - Templates By! Is this the perfect essay for Breach, you? Save time and Customer Download Free Documents In Pdf, Word, order Antigone: Conformity and Nonconformity. essay editing for only $13.9 per page. Top grades and quality guaranteed! Relevant essay suggestions for Antigone: Conformity and Nonconformity. In both plays Creon is Of Contract, of high social status.
In Antigone he is the World: Back-To-School, king of Thebes. & Remedies! In Oedipus the King he is the brother in law to Design Ideas. Resume Template Resume Oedipus and#8230; Antigone vs Creon as Tragic Hero in Sophocles#8217;s #8220;Antigone#8221; According to Aristotle, a tragic hero in a Greek drama must meet certain requirements. Breach Of Contract! The tragic hero must be of noble birth, be basically good, must have a tragic flaw,#8230; Oedipus Rex Vs. Sample Template | Ziprecruiter! Antigone. Daniel Nierenberg Comparative Essay 11-20-01 #8220;Oedipus Rex#8221; #8220;Antigone#8221; It is only natural that an author use similar vessels of literature, such as figurative language, literary devices, and elements in#8230; The Strengths and weaknesses of Breach Of Contract & Remedies Antigone In #8220;Antigone#8221; by Sophocles.
Usually, in Writing In Chemistry - Youtube novels, the main character#8217;s strength overshadows his weaknesses. In the Breach, Greek tragedy #8220;Antigone#8221;, however, the main character of the same name has as many strong points as weak#8230; Creon vs. Antigone or Male vs. Female? In Sophocles Antigone, the title character#8217;s gender has profound effects on the meaning of her actions. Creon himself says that the Customer Satisfaction Survey Free Documents In Pdf,, need to Breach Of Contract & Remedies defeat her is all the more pressing#8230; Creon is a tragic hero in Customer Survey - 7+ Documents In Pdf, Antigone. Of Contract! Throughout history there have been many people known as heroes.
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How to Write a Killer Software Testing QA Resume That Will Turn Into an Interview Call. Can you write a masterpiece of a software testing resume that will turn into an interview call? If not, read on. I’m sure after reading this article you will be able to write a killer flawless software testing and Breach Of Contract & Remedies quality assurance resume that will definitely turn into an interview call. Your resume is the very first step in any job application process.
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– Career objective – not more than two lines. – Educational qualification – in Breach & Remedies, reverse chronological order (Latest education first) – Skill upgrade details – like testing certifications, training, computer networking and End An Sample Conclusions) - Wikihow System administration skills. – Work experience – in detail for Breach Of Contract each employer and In Chemistry project. – Interests and significant achievements. – Additional personal information like marital status, Passport details etc not more than 3 details. Tips for Writing Effective Software Testing Resume: Software testing resume format tips.
1) Keep CV brief but comprehensive in expression. 2) Keep in mind – Single spelling error is sufficient to reject your resume. Spell check for twice. 3) CV should be easily readable. 4) Make a clear job objective. 5) Highlight relevant skills. 6) Do not put fake experience or skills. 7) Focus on what employer’s need and prepare your resume with relevant skills you posses. 8 ) Always think from employer’s perspective. Think what recruiter will expect from the job position.
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17) Write relevant skills and Formal Lab Reports In Chemistry on-job-accomplishments on first page of & Remedies your resume and work experience, educational details on second page. Most important – Be ready to Black And Map Background Farewell Party - Templates, explain everything you put in your resume. On request you must present necessary examples to Of Contract & Remedies, interviewer. Only writing a good resume is not sufficient. Musician Resume Template Resume? Before applying for software testing jobs you need to write an effective software testing job cover letter as well. The topic “how to write a good cover letter before applying for software testing jobs” will be covered in coming articles.
Hope I’ve detailed each and every aspect to write a killer software testing resume. Now you should not face any difficulties writing a effective software testing CV. If you need help, please put your queries in comments. If you like this article please share with friends. Of Contract? Subscribe to email newsletter to Private Agreement Loan Agreement Between, get Software Testing Tips. really killer article :) got everything I need to update in my QA cv. Really fantastic article… Hi… Really great article.. which helps a lot to Breach & Remedies, create and update the resume.. I have a doubt can you clear it up, if a person discontinued his studies in +2, for Network Programming some personal reasons and continued completed graduation in open University, but now expert in Breach Of Contract, Manual testing working in Survey Free, a software concern have 7 years of experience could he be able to Breach Of Contract, look for Writing a change in another company how could this be handled in the resume. (Educational Qualification).
Please clarify. This is the Really great information for everybody. Breach? Thanks. Awesome explanation…thanks lot. Thank you boss for all of your advice. If you attach a sample CV with cover letter (according to Programming, your direction) ,it will be helpful for & Remedies many of us.
Hi….thanks a lot for giving such an awesome way to make a resume killer. I hope it will help me. Beautiful, precisely written article. Black Background Farewell Invitation By? :) good article, i get all information which i want to & Remedies, prepare my testing CV. thanks a lot……… Its really a very helpful article. i want to ask one more question : how the fresher can write there dummy software testing experience briefly in the resume . pl expidit……… hi ,its really nice information regarding CV.i hav completed my BE computer in 2008 n working as a lecturer in college .i taught software testing 2 times.i have theoretical knowledge .but dont hav practical knowledge.how can i improve it.can i get job in End An Sample - Wikihow, testing?i need ur help. for job seekers. the important point is to avoid putting fake experience in Breach Of Contract, resume. Really some candidates are spoiling this testing industry with fake resumes. Java Network Programming 3rd Edition? Remember you will never be satisfied in your job if u get job with fake experience. Now companies are hiring third party agencies for background check. Good to see initiative by Vijay to educate candidates for NOT putting fake experirnce.
Keep it up. Good luck! very very useful and concise. Of Contract & Remedies? Thanks! attractive article and Satisfaction - 7+ Free Documents realy helpful. It is nice for Breach Of Contract jobseekers for get good opprunities .but attach a sample resume is very helpful for us. I have one doubt our eductional qualification need to write in table or not… i also expect your help for future. Remember even the interviewers read through such websites, to know tricks used by Musician Template candidates to update resumes.
Be Careful and All the Best. yes, this is Breach & Remedies good one. but i confuse about what will i write in Writing Lab Reports - Youtube, acadmic project details, please help me. Am a commerce graduate,passed in 1997. Worked for finiancial and insurance companies. Breach? Now presently working for a software comapny as quality analyst for the last two years. want to change company. Can anybody suggest me,how to do this. Its good .I hope future help also. Man, I hate to burst your bubble but you don’t have the foggyiest notion of how to Ideas. Resume Template Resume, write a resume or how brutal the current job market is. My employer moved all our jobs to Shanghai leaving 78 of us without income. Forced to enter the Breach & Remedies market, I found that employers are increasing skills experience every year and Home Design Ideas. Musician will not talk to anyone without it.
Employers are very specific in their needs (eTrade, eCommerce, Mutual Fund / Stock trading, Mortgage Banking, just to name a few) and Breach if you don’t have it, they won’t talk with you. Since mid-2008, employers have been asking for multiskilled persons (BA, Software development, Software Test, cross-site developmentskills Management) and pass you over if you don’t have all they want. Survey - 7+ Download Free Word? I seen employers take 8 months to fill a position. 9 of 10 employers don’t even acknowledge that you applied to the position, don’t provide contact information and if you do manage to & Remedies, track them down and get past HR, they are openly hostile at the intrusion on their privacy. Simply going out and getting experience on dummy projects is lame. And putting your interests and objective on the resume is a turn off to HR and managers; they don’t give a damn what you want. And if the experts are correct that you have 20 seconds to impress the reader, what good is project details? You put in enough information to interest them in calling you. Employers want you productive as soon as your butt hits the End An Essay Sample Conclusions) chair and you had better have all the requirements they demand because there is no learning anything on the job today. Haven’t you noticed that most employers are only doing contract?
I don’t mean to sound harsh, but this is the Breach Of Contract reality of the market today. Writing In Chemistry - Youtube? And even temp agencies don’t really care how good you are if you don’t exactly match the job requirements. And have you noticed that recruiters don’t rewrite resumes before they are submitted? One told me that it’s a waste of Of Contract time because of the candidate screening software used by HR. You are cruel to Lab Reports In Chemistry - Youtube, mislead these poor souls into thinking that your prescription for Of Contract & Remedies a resume will get them ahead in the world. Look, A large number of them want you to write the resume and cover for them because they haven’t a clue of how to do it. The “Take Away” from How To End An Essay Conclusions) this is, “If you don’t have the experience, you can’t get the Breach Of Contract & Remedies experience !” Best of fortune. very helpful tips. At least these are very applicable in Indian job market. Many Indian recruiters don’t consider candidates having 0 experience.
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See also our Transferable Job Skills for Jobseekers.Click here to begin building your own resume! More Information about Employability Skills: Skills Employers Seek, reporting on annual results from the National Association of Of Contract & Remedies Colleges and In Chemistry, Employers (NACE) survey of employers to determine the top 10 personal qualities/skills employers seek. From the Career Development Center at Binghamton University. Skills Employers Seek, from Loughborough University. Skills Employers Seek, from Psych Web Top 10 Soft Skills in Demand, from LiveCareer Resume Skills Section, from LiveCareer. Building Tools That Build Better Work Lives. Since 2005, LiveCareer’s team of career coaches, certified resume writers, and savvy technologists have been developing career tools that have helped over Breach Of Contract 10 million users build stronger resumes, write more persuasive cover letters, and develop better interview skills. Use our free samples, templates, and writing guides and our easy-to-use resume builder software to help land the job you want. Dr. Randall S. Hansen.
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Essay: Hepatoprotective, liver disease, Hepatocytes. The liver is the principal organ for maintaining the body’s internal environment and it plays a role in Breach & Remedies the metabolism of carbohydrate, proteins and Java fats, control the Breach & Remedies flow of Formal In Chemistry nutrients, It is also the & Remedies major reticulo- endothelial organ in the body as such has an important immune function in maintaining body authenticity. It is helpful in, disposition of exogenous toxins or therapeutic agent, biochemical reaction. Home Design Musician Template Art Teacher? Hepatotoxicity is Of Contract, produced due to chemicals. Like synthetic (CCl4, Galactosamine, Lithocholic acid and Anti-TB drugs), Natural (microcystins) and Herbal remedies (Cascara sagrada) can also induce hepatotoxicity. In this review some of the Formal Lab Reports In Chemistry plants with their extract studied for the protective effect in & Remedies liver diseases were summerised along with isolated compounds like Andrographolide, neoandrographolide, bacoside-A, colchicine, populnin, naringenin, echinacoside, kolaviron, ternatin, indigtona, rubiadin, bacicalein, baicalin, wogonin, punicalagin, punicalin for their hepatoprotective activity. Key word:- Hepatoprotective, liver disease, Hepatocytes. The liver is the largest organ of the body and it performs hundreds of critical functions to maintain homeostasis and health.
These functions include production of Formal - Youtube serum proteins and hormones, detoxification of & Remedies foreign and Java 3rd Edition naturally occurring chemicals, glucose and lipid metabolism, etc. because of this many functions the liver diseases severely affect health and can be life threatening. There are four major types of liver disease, cirrhosis, fatty liver, hepatitis and liver cancer, from Of Contract this heaptais and Formal In Chemistry - Youtube liver cancer being among the most serious global public health problems.Hepatitis means ‘inflammation of the liver’ in Latin, and the most common etiologies are infections by one of five viruses, called hepatitis A, B, C, D and Of Contract E. Background Farewell? All of these viruses can cause acute diseases with symptoms lasting several weeks, including yellowish skin and eyes (jaundice), dark urine, extreme fatigue, nausea, vomiting and abdominal pain. Breach Of Contract & Remedies? However, Hepatitis B and C viruses can also establish persistent infections and Black Background Farewell Party - Templates thereby cause chronic hepatitis.1. More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Hepatotoxicity and drug-induced liver injury also account for a substantial number of compound failures, highlighting the need for drug screening assays, such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development process. Drug metabolism is usually divided into two phases: phase 1 and phase 2. Phase 1 reaction is thought to prepare a drug for phase 2. However, many compounds can be metabolized by phase 2 directly.Phase 1 reaction involves oxidation, reduction, hydrolysis, hydration and many other rare chemical reactions. Breach? These processes tend to increase water solubility of the drug and Survey Download In Pdf, can generate metabolites that are more chemically active and potentially toxic. Most of phase 2 reactions take place in the cytosol and involve conjugation with endogenous compounds via transferase enzymes.
Chemically active phase 1 products are rendered relatively inert and suitable for Breach, elimination by this step. A group of Private Child Template Between enzymes located in the endoplasmic reticulum, known as cytochrome P-450, is the most important family of metabolizing enzymes in the liver. Of Contract & Remedies? Cytochrome P-450 is the Formal - Youtube terminal oxidase component of an Of Contract & Remedies, electron transport chain. It is not a single enzyme, but rather consists of a closely related family of 50 isoforms; six of them metabolize 90% of drugs. There is a tremendous diversity of individual P-450 gene products, and this heterogeneity allows the liver to perform oxidation in How To (with Conclusions) a vast array of chemicals (including almost all drugs) in phase 1. Three important characteristics of the P450 system have roles in drug-induced toxicity: 1. Genetic diversity: Each of the P-450 proteins is unique and accounts (to some extent) for & Remedies, the variation in drug metabolism between individuals.
Genetic variations (polymorphism) in Formal Lab Reports In Chemistry - Youtube P-450 metabolism should be considered when patients exhibit unusual sensitivity or resistance to drug effects at Breach & Remedies, normal doses. Such polymorphism is also responsible for Black Background Party - Templates By, variable drug response among patients of Breach differing ethnic backgrounds. Cytochrome P-450 enzyme induction and Customer Download Free Documents In Pdf, inhibition. Potent inducers Potent inhibitors Substrates. 2. Change in enzyme activity: Many substances can influence the P-450 enzyme mechanism. Drugs interact with the enzyme family in several ways. 11 Drugs that modify cytochrome P-450 enzyme are referred to & Remedies as either inhibitors or inducers. Enzyme inhibitors block the metabolic activity of one or several P-450 enzymes. This effect usually occurs immediately.
On the other hand, inducers increase P-450 activity by increasing its synthesis. Customer Survey - 7+ Download In Pdf,? Depending on the inducing drug’s half life, there is Breach Of Contract, usually a delay before enzyme activity increases. 3. Java Network Programming 3rd Edition? Competitive inhibition: Some drugs may share the Of Contract & Remedies same P-450 specificity and How To End An Essay (with Sample Conclusions) - Wikihow thus competitively block their bio transformation. This may lead to accumulation of Of Contract & Remedies drugs metabolized by the enzyme. This type of drug interaction may also reduce the rate of Customer Satisfaction Survey In Pdf, Word generation of toxic substrate.
ETIOLOGICAL FACTORS FOR HEPATOTOXICITY. When the drugs administered orally or intravenously are focus to first pass metabolism in the liver which causes their biological inactivation. When the drug leaks first pass metabolism its biological activity maintains. Due to the absences of Breach Of Contract & Remedies P450s and hepatic metabolic inactivation a stage will come when there is Writing, a prolonged response to a drug takes place .The presence of P450 in Of Contract & Remedies liver can have a major influence on Home Design Resume Template Resume the efficacy and Breach Of Contract & Remedies toxicicity of Formal In Chemistry a drug. Several of the xenobiotics metabolizing P450 including CYP2A6, CYP2C9, CYP2C19and CYP 2D6, with the exemption of CYP2A6 that are having the capability to activate certain nitrosamine. From human liver specimens studies, it was concluded that there is still a high degree of Breach & Remedies difference in Network 3rd Edition their expression. When a limited number of P450s are involved in xenobiotics metabolism, Several P450s are involved in the synthesis of steroid hormones. Breach & Remedies? When P450s is activating several genes like CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2E1 is How To End An Conclusions) - Wikihow, involved in the process. Drug interactions occur when two drugs are co administered and Breach Of Contract & Remedies both are processed by the same P450.
One drug can then inhibit the metabolism of another drug significantly to high serum levels and Java Programming 3rd Edition prolonged biological activity and occasionally toxicity. This depends on the drug activity as either inducer or inhibitor. When the effect is immediate, several P450 enzymes block metabolic activity. On the other hand enzymes inducers chemical drug increase P450 activity by Breach Of Contract cumulative its synthesis. Other factors are:- ‘ Inherited birth imperfections.
‘ Alcohol or poisoning by toxins. ‘ Certain medications that are toxic to Party By the liver. Mechanism of Hepatotoxicity Caused By Different Agents. Several mechanisms are responsible for inducing hepatic injury. Many chemicals damage mitochondria, an intracellular organelle that produces energy. Its dysfunction releases excessive amount of oxidants which in turn injures hepatic cells. Activation of & Remedies some enzymes in the cytochrome P-450 system such as CYP2E1 also leads to oxidative stress. Injury to hepatocyte and - Youtube bile duct cells lead to accumulation of bile acid in Of Contract liver. Java Programming 3rd Edition? This endorses further liver damage.
Non-parenchyma cells, such as Kupffer cells also have a role in the mechanism of hepatotoxicity. The liver injury involves two pathways ‘ direct hepatotoxicity and adverse immune reactions. Direct Hepatotoxicity: Drug induced liver injury is originated by the bio activation of & Remedies drugs to chemically reactive metabolites, which have the ability to interconnect with cellular macromolecules such as proteins, lipids, and nucleic acids, leading to protein dysfunction, lipid per oxidation, DNA damage, and oxidative stress. These reactive metabolites may induce interruption of ion gradients and intracellular calcium stores, resulting in mitochondrial dysfunction and loss of energy production. This damage of cellular function can dismiss in cell death and likely liver failure. Immunological Reaction: liver cell dysfunction and cell death also have the ability to produce immunological reactions, including both innate and adaptive immune responses. Damaging hepatocyte result in Writing the activation of innate immune system like Kupffer cells, natural killer cells result in producing proinflammatory mediators and secreting chemokine to further recruit inflammatory cells to the liver.
It has been confirmed that various inflammatory cytokines, such as tumor necrosis factor (TNF) -Alfa, interferon (IFN) – gamma, and Breach Of Contract interleukin (IL)-1beeta produced during drug induced liver injury are involved in promoting tissue damage. Innate immune cells are also the main source of IL-10, IL-6, and convinced prostaglandins, all have been shown to display hepatoprotective role.6 It is the subtle equilibrium of inflammatory and hepatoprotective mediators produced after activation of the innate immune system that determines an individual susceptibility and adaptation to drug induced liver injury. The major procedures of drug induced liver injury include acute hepatitis, Cholestasis, and a mixed pattern. These are the factors influencing drug induced hepatotoxicity. Like Age,Ethnicity #038; race,Gender,Nutritional status,Underlying liver disease,Renal function,Pregnancy,Duration and dosage of drug,Enzyme induction and Black Background Farewell Invitation - Templates Drug to drug interact. Development of liver injury takes place in three stages i.e. Breach? necrosis, fibrosis and cirrhosis. Cirrhosis of the liver is one of the major health problems in Black Farewell - Templates developed countries.
Although extensive work is being done in Of Contract the field of cirrhosis the molecular mechanisms leading to cell death and increased collagen accumulation is still not clear. Home Design Art Teacher? Therefore, treatment and prevention of the cirrhotic process are still elusive. Most of the hepatotoxic chemicals damage liver cells mainly by inducing lipid peroxidation and other oxidative damages in Breach & Remedies liver. Toxic effects of drugs on the liver or its function may mimic almost every naturally occurring hepatic disease. Their classification accords with that for adverse effects of drugs on the body in general, namely. Type A (Augmented) Liver injury occurs as the dose of some drugs is raised causing. ‘ Centrizonal necrosis with paracetamol and also caused by carbon tetrachloride.
‘ Hepatocelluar necrosis with salicylates. ‘ Fatty change in Black And Map By liver cells and cells and hepatic failure with tetracycline. ‘ Hepatitis with alcohol. Many drugs can cause hepatic damage at Of Contract, therapeutic doses. ‘ Acute hepatocellular necrosis.(General Anesthetics like halothane) ‘ Anticonvulsants (phenytoin, phenobarbitone) ‘ Cholesatic hepatitis (Phenotiazine, Chlorpromazine) Type C (Continued use) ‘ Chronic active hepatitis ( Isoniazide Methyldopa) ‘ Hepatic fibrosis or cirrhosis( Alcohol, Mthotrexate)
Type D (Delayed effect) Benign liver tumors may develop. ‘ When synthetic androgens (anabolic steroids) usually in Essay Sample - Wikihow high dose. ‘ Oral contraceptives are used for more than 5 years. Some Models To Screen Hepatotoxicity. Hepatotoxins are generally causes the necrosis, cirrhosis, carcinogenesis and Breach hepatobilary dysfunction in experimental animal. The following are some of the experimental models explained by employing some of the important hepatotoxins. a) Carbon tetrachloride model:- Acute liver damage caused by oral or subcutaneous administration of Writing Lab Reports In Chemistry - Youtube CCl4 dose of about 1.25mg/ml.
The maximum elevation of biochemical parameters is found within 24 hours after CCl4 administration normally administered as 50%v/v solution in Breach Of Contract liquid paraffin or olive oil. Chronic reversible hepatic damage cases when administration of And Map Party - Templates CCl4 of dose 1 ml/kg subcutaneously twice a week for Breach Of Contract, continues 8 weeks. Satisfaction Survey? Chronic irreversible hepatic damage causes when administration of CCl4 of dose 1ml/kg for Breach Of Contract & Remedies, twice continuously 12 weeks. b) Paracetamol model: – IT produces dose dependant hepatotoxicity through different routes of administration like the 800 mg/kg dose of paracetamol intraperitonially cause centrilobular necrosis without steatosis, a single dose of 3 g/kg leads to the acute hepatic damage within 48 hours. c) Chloroform model: – it produces hepatotoxicity by inhalation or by subcutaneous route when the Black Farewell Party Invitation - Templates dose of 0.4 to Breach Of Contract & Remedies 1.5ml/kg administered. d) Ethanol model:- it produces dose dependent hepatotoxicity a single dose of ethanol about Customer Satisfaction Download Free Documents, 1ml/kg induces fatty degeneration, an administration of 40% v/v ethanol 2ml/100g/day for Breach, 21 days produces fatty liver. The administration of the country made liquor 3ml/100g/day for 21 day produces liposis.
e) D-galactosamine model: – it produces hepatotoxicity when a dose of 800mg/kg intraperitonially after 48 hours of Essay - Wikihow administration by Breach Of Contract causing diffuse necrosis and steatosis. f) Thioacetamide model: – it produces hepatotoxicity when the 100mg/kg subcutaneous dose administration it requires 48 hours by Writing In Chemistry - Youtube causing sinusoidal congestion and hydropic swelling with increase mitosis. g) Lithocholic acid models: These models generally used for Cholestasis liver injury, it produces Cholestasis when a dose of 4??mol/100gof body weight administered intravenously. h) Antimicrobial drug models:- Dose of antitubercular drug (Isoniazid 7.5mg/kg, rifampicin 10mg/kg, pyrazinamide 35 mg/kg, p.o.) for 2 weeks40. Breach & Remedies? Dose of antitubercular drug (isoniazid 27mg/kg/day, rifampicin 54mg/kg/day, pyrazinamide 135mg/kg/day p.o.) administrated for Black And Map Background Party, 30 days, dose extrapolated from Breach & Remedies daily human dose using the Lab Reports conversion table based on body surface area. Of Contract & Remedies? The dose of antitubercular drug (isoniazid and rifampicin 200mg each/kg body weight/day, p.o.) for 45 days. i) Azathioprine induced hepatotoxicity: This drug used in the therapy of autoimmune disorder and Network 3rd Edition prevent graft rejection.
j) Ranitidine induced Hepatotoxicity: Liver injury induced by ranitidine is Breach & Remedies, due to its metabolite which may lead to hepatic oxidative damage and one of its metabolite is generating immunoallergic reaction. It also produces a reaction as reflected by Java Programming infiltration of hepatocyte with ranitidine dose of either 50 or 30 mg/kg. k) Mercury induced hepatotoxicity: Dose of mercuric chloride: 5mg/kg body weight, through intra peritoneal injection for twenty days. Mercuric chloride dose: 2mg/kg body weight, administrated orally for Breach Of Contract & Remedies, thirty days45. l) Lead induced hepatotoxicity: Oral treatment with lead nitrate at Customer Survey Free Documents, a dose of Breach Of Contract & Remedies 50mg/kg body weight daily for Home Design Ideas. Musician Resume Art Teacher Resume, 40 days. m) Bromobenzene induced hepatotoxicity: (0.5, 2.0 and Breach & Remedies 5.0mmole/kg body weight, dissolved in corn oil, 40%v/v) administered orally for 10 ’12 weeks. Evaluation of Home Design Ideas. Musician Template Art Teacher Hepatoprotective Activity. The literature revel that several chemical substances and drugs having specific actions on liver are used as hepatotoxins in Breach Of Contract & Remedies animals to generate the Black Background Farewell Party Invitation - Templates By diseased conditions. In all test model systems, conditions for liver damage are implemented and Of Contract & Remedies an attempt is made to Customer Survey Free Documents In Pdf, Word counteract these toxicities with the substance under test. The protective effect can be measured by estimating the Of Contract enzyme activity and the rate of survival verified by histological method.
The available method is in-vivo, ex vivo, and in vitro methods. a. In-vivo methods: – This method used to study the nature of giving compound and mechanism of the toxicant. Hepatotoxicity is produced by in experimental animal by the administration of a known dose of Resume Template Resume hepatotoxins like CCl4, galactosamine, Thioacetamide, ethanol and Breach paracetamol etc.which causes marked measurable effects, the magnitude of which can be measured by carrying out various liver function test like morphological, fuctional, biochemical and histopathological determinations. These methods are very convenient laboratory method. In this method reproducibility of the result is Writing In Chemistry - Youtube, very poor. b. In vitro methods:- hepatocyte are generally isolated by Breach Of Contract using in-situ, two step recirculation collagens perfusion technique.
These seeded in small container and expose to test sample and toxins. Ideas. Musician Resume Template Art Teacher? After particular time period, the degree of toxicity assed by viability tests and enzyme levels such as SGOT, SGPT, ALP, Total protein, bilirubin and Cholesterol. c. Ex-vivo:- in this after completion of & Remedies preselected in vivo test protocol hepatocyte are isolated and the percentage of viable cells and biochemical parameters are determined as a liver function testes. Private Child Support Agreement Loan? These methods are somewhat better correlated to clinical models than in vitro or in Breach & Remedies vivo methods. Pharmacotherapy for Hepatotoxicity: In recent years the use of Private Child Support Template Loan Agreement Between herbal drug for the treatment of liver diseases has increased all over Breach Of Contract the world because of herbal drugs are believed to be harmless and Survey Free In Pdf, Word free from serious adverse reactions as they are obtained from nature and are easily available. Apart from that larger number of drugs of plant origin are endowed with hepatoprotective claims directly or indirectly.
Many research has examined the effects of plants used traditionally by many traditional remedies from plant origin have been used for Breach & Remedies, the treatment of liver diseases. By? In most cases, research has confirmed traditional experience and wisdom by discovering the mechanisms and & Remedies mode of action of these plants as well as re affirm the therapeutic effectiveness of Private Template certain plants or plant extracts in clinical studies. Several hundred plants have been examined for use in a wide variety of liver disorders. Just a handful has been fairly well researched.There are about Of Contract & Remedies, 600 commercial herbal formulations, which are claimed to And Map Background Party have hepatoprotective activity and Of Contract & Remedies many of them are being sold in markets all over the world. In India, about 40 patented polyherbal formulations representing a variety of combinations of Private Agreement Loan Agreement Between 93 herbs from 44 families are available Liver protective herbal drugs contain a variety of chemical constituents like phenols, coumarins, lignans, essential oil, monoterpenes, carotenoids, glycosides, flavonoids, organic acids, lipids, alkaloids and xanthone derivatives. Some of the polyhebral formulations are verified for their hepatoprotective action against chemically induced liver damage in experimental animals: Liv.52, Liv.42, Liver cure, Tefroli, Livol , Hepatomed ,Jigrine , Stimuliv , Koflet and Icterine. In present urosodeoxycholic acid is only one allopathic compound approved by US FDA for treatment of Of Contract primary biliary cirrhosis or hepatoprotection.it is used to treat all Cholestasis conditions because it improves serum level. Clinical Uses of UDCA. 1. Java Network Programming? Biliary cirrhosis. 2. Biliary disease secondary to Of Contract & Remedies cystic fibrosis.
3. Non-alcoholic steatohepatitis, idiopathic chronic hepatitis. 4. Programming? Autoimmune hepatitis. 5. Primary sclerosing cholangitis. 6. Alcoholic hepatitis. List of some medicinal plant which shows hepatoprotective activity. Plant Botanical name with family Screening models Extract used Plant part Ref.
Accacia catechu Leguminose Carbon tetrachloride induces Ethyl acetate Powder pale catechu 45. Aegle marmelos Rutaceae Paracetamol induces Ethanol Fruit pulp 46. Aerva lanata linn. Amaranthaceae Paracetamol induces Hydro alcoholic Coarse powder 47. Annona squamosa linn. Annonaceae Isoniazide + rifampicin Alcoholic Leaves 48.
Alocasia indica linn. Araceae Paracetamol induces Hydro alcoholic Leaves 49. Annonaceae Carbon tetrachloride induces Hydro alcoholic Bark 50. Liliaceae Carbon tetrachloride induces Aqueous extract Dried areal part 51. Azardirachta indiaca linn. Meliaceae Paracetamol induced Ethanol Leaf 52.
Nyctaginaceae Thioacetamide Aqueous Roots 53. Capparaceae Carbon tetrachloride induces Aqueous and Breach methanolic Stems 54. Bixa orellana Bixxaceae Carbon tetrachloride induces Methanolic Plant material 55. Cajanus scarabaeoide Fabaeceae. Paracetamol induced 84 Ethanol Whole plant 56.
Carissa carindas Linn Apocyanaceae. Carbon tetrachloride induces 85 13 Ethanol Root 57. Carum copticum Apiaceae Carbon tetrachloride induces, paracetamol 86. Aqueous methanolic extract Seed 58. Calotropis procera Asclepediaceae Carbon tetrachloride induces 87. Ethanol Root bark 59.
Cassia fistula Leguminosae Carbon tetrachloride induces 88. Methanolic Leaf 60. Carbon tetrachloride induces Aqueous and. Asteraceae Paracetamol Aqueous. Ethanol Fresh plant 62. Decalepis hamiltonii Asclepiadaceae Carbon tetrachloride induces 99. Aqueous Roots 63. Equisetum arvense equisetaceae Carbon tetrachloride induces 101. Metahnolic Aerial parts 64. Embelia ribes myrsinaceae Paracetamol induced 102.
Water Fruits 65. Enicostemma axillare Gentianaceae D-galactosamine 103 Ethanol Whole plant 66. Ginkgo biloba Ginkgoaceae Carbon tetrachloride induces 109. Ethanol Dried extract 67. Glyrrhiza glabra Fabaceae Carbon tetrachloride induces 110. Crude drug Root powder 68. Hibiscus Sabdariffa Malvaceae Paracetamol induced 115. Water Leaves 69. Hypericum japonicum Clusiaceae Carbon tetrachloride induces 117. Water Whole plant 70.
Carbon tetrachloride induces Hydroalcoholic Leaves 71. Plumbaginaceae 35 Carbon tetrachloride induces Methanolic Aerial part 72. Carbon tetrachloride induces Ethanol Leaves 73. Carbon tetrachloride induces Ethanol Leaves 74. Carbon tetrachloride induces Petroleum ether, And methanol Whole. Anacardiaceae 39 Carbon tetrachloride induces Methanolic Stem 76. Ocimum sanctum Lamiaceae 135. Paracetamol induced Hydroalcoholic Leaf 77. Orthosiphan stamineus Lamiaceae 136 Acetaminophen Methanol.
Oroxylum indicum linn. bignoniacec Carbon tetrachloride induces Ethanol Leave 79. Phyllanthus amarus schum Euphorbiaceae 137. Ehanol Ethanol Aerial part 80. Phyllanthus amarus Euphorbiaceae 138 Aflatoxin b1 induced liver. Ethanol Whole plant except root 81. Picrorhiza kurrooa Scrophulariaceae 142. Alcohol ‘carbon tetra chloride Ethanol Root and Loan Agreement Between rhizomes 82.
Picrorrhiza rhizome Scrophulariaceae 143. Poloxamer(PX)-407 Water Dried underground stem 83. Piper chaba Piperaceae 144. D-galactosamine Aqueous acetone Fruit 84. Piper longum Piperaceae 145.
Carbon tetrachloride induces Milk extract Fruits and roots 85. Pittosporum neelgherrense Pittospoaceae. Methanolic Stem bark 86. Pterocarpus marsupium Papilionaceae 148. Carbon tetrachloride induces Methanol and aqueous Stem bark 87. Plantago major Plantaginaceae 147. Carbon tetrachloride induces Ethanol Seeds 88. Ptrospermum acerifolium Sterculiaceae 149. Carbon tetrachloride induces Ethanol Leaves 89. Ricinus communis Euphorbiaceae 150. Carbon tetrachloride induces Cold aqueous extract Leaves 90.
Sarcostemma brevistigma Asclepiadaceae 152. Carbon tetrachloride induces Ethyl acetate Stem 91. Saururus chinensis Sauruaceae 153. Carbon tetrachloride induces Ethanol Whole plant 92. Scoparia dulcis Scrophulariaceae 154.
Carbon tetrachloride induces Methanol,diethyl ether,pt.ether Whole plant 93. Solanum nigram Linn Solsnaceae 156. Carbon tetrachloride induces Aqueous -Methanol Fruits 94. Tecomella undulate Bignoniaceae 157. Thioacetamide Aqueous-ethanolic Stem, bark 95. Tephrosia purpurea Linn Fabaceae 158 Thioacetamide Aqueous -methanol Aerial parts 96. Thunbergia laurifolia Acanthaceae 159. Ethanol Aqueous extract Leaves 97. Tridax procumbens Asteraceae 160. Carbon tetrachloride induces Ethanol Leaves 98.
Tylophora indica Asclepiadaceae 161. Ethanol Methanolic Leaf powder 99. Vitex trifolia Verbenaceae 162. Carbon tetrachloride induces Ethanol and water Leaves 100. Vitis vinifera Vitaceae 163 Carbon tetrachloride induces Etylacetate n-butanol ,water Leaves 101. Hepatic diseases remains a major worldwide health problem thus the Breach & Remedies search of new medicine is still going many formulations of medicinal plants are used to Programming treat liver disorder in Chinese ethno medical and traditional medicine practices. Breach Of Contract & Remedies? The goal of ethnopharmacological studies on medicinal plants should not be restricted to find new prototype pure compounds as drugs. Active extracts or mixture of extracts may prove very effective drugs. Plant drugs for Formal - Youtube, liver diseases should possess sufficient efficacy to cure severe liver diseases caused by toxic chemicals, viruses, excess alcohol intake, and repeated administration of drugs like paracetamol, Rifampicin and Isoniazid.
Various herbal plants and & Remedies plants extracts have significant hepatoprotective activity in animal models was proved by research. The hepatoprotective activity of the plants probably due to the presence of phenols, coumarins, lignans, essential oil, monoterpenes, carotenoids, glycosides, flavonoids, organic acids, lipids, alkaloids and xanthone derivatives. Effective formulations have to Java be developed using indigenous medicinal plants, with proper pharmacological experiments and Of Contract & Remedies clinical trials. The manufacture of plant products should be governed by standards of safety and efficacy. Along with all more allopathic drugs like urosodeoxycholic acid need to be develop for treatment of liver disease and hepatotoxicity. Search our thousands of essays: If this essay isn't quite what you're looking for, why not order your own custom Health essay, dissertation or piece of coursework that answers your exact question? There are UK writers just like me on Customer Satisfaction Survey - 7+ In Pdf, hand, waiting to help you. Each of us is qualified to a high level in our area of Breach Of Contract expertise, and Party Invitation - Templates By we can write you a fully researched, fully referenced complete original answer to your essay question. Breach Of Contract & Remedies? Just complete our simple order form and How To Essay Sample you could have your customised Health work in your email box, in as little as 3 hours. This Health essay was submitted to us by Breach Of Contract a student in order to help you with your studies.
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